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System Represents Significant Advancement in Accuracy in Disposable Sensors

Finesse Solutions, LLC, a manufacturer of measurement and control solutions for life sciences process applications, announces the release of TruFluor(TM), a single use optical dissolved oxygen measurement system, at Interphex in Philadelphia on March 26, 2008.

The TruFluor(TM) dissolved oxygen and temperature sensor is a single-use solution consisting of a disposable sheath, an optical reader, and a transmitter. The single-use sheath can be pre-inserted in a disposable bioreactor bag port, and irradiated with the bag, in order to both preserve and guarantee the sterile barrier. All wetted materials of the sheath are USP class VI compliant.

According to Finesse Solutions' CTO, Dr. Mark Selker, "The TruFluor system represents a significant advancement in accuracy, lifetime, and ease of use in disposable sensors for bio-processing. Every aspect of the product has been engineered with the thought of reducing time, overhead, and the risk of sterility breaches."

The optical reader uses advanced optical components including a large area photodiode that minimizes photo-degradation of the active sensing element. The design has been optimized to provide accurate, in-situ measurement of dissolved oxygen using phase fluorometric detection in real-time. The temperature measurement leverages a 316L stainless steel thermal window embedded in the sheath, and provides a highly accurate temperature measurement that can be used as a process variable.

The TruFluor(TM) DO Transmitter optimizes the performance and reliability of the TruFluor(TM) Dissolved Oxygen Sensor by enabling automatic entry of calibration and traceability data using RFID, diagnostics, and verification. The calibration and lot data is encoded on a gamma radiation resistant RFID tag attached to the disposable sheath through production. This tag is automatically read by the transmitter, thereby eliminating the need to calibrate the probe and minimizing error and variability in the calibration.

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