Leica Microsystems, a global provider of scientific instruments and microscopes, has introduced a new digital microscope camera, the Leica DFC365 FX fluorescence camera designed for imaging of live cells.
A camera specifically designed for effectively documenting live cells and fluorescence specimens that rapidly fade would be an indispensable tool for the scientific community. The new Leica camera is suitable for a broad range of applications including structured, FRET and TIRF illumination and fluorescence documentation.
The Leica DFC365 FX features high temporal resolution and image quality for quick time-lapse recordings. It allows researchers to acquire images even from weakly fluorescing specimens. It can acquire images at ultra high-speeds of 40 MHz. The camera also has active Peltier cooling and a sensitive CCD sensor with a pixel size of 6.45 µm.
Fluorescence markers that emit in a wavelength of over 700 nm cannot be easily captured using conventional CCD technology. The Leica camera features an optional near infra-red mode that can extend the camera’s operating range. At full resolution, the camera has an acquisition rate of 21 fps.
The Leica DFC365 FX has an "Overlapping Mode" that allows capture of a new image even when a previously existing image is being read out. The sensor’s pixel clocking rate can be set as 1.6 MHz or 20 MHz according to the requirement. This enables delivery of brilliant fluorescence images with a good signal-to-noise ratio. The camera features a FireWire-B interface that allows rapid transfer of data to a PC.