Jun 23 2011
AIS introduces Spectral karyotyping (SKY®) equipment, designed and manufactured by ASI, a leading developer of comprehensive solutions for pathology and cytogenetics. Spectral karyotyping (SKY®) is ASI’s novel addition to the cytogenetic tool kit.
It is based on a unique electro-optical hardware that enables measuring the spectral image of a metaphase, previously stained, such that each chromosome class has a different color (created typically from different combinations of 5 or more basic dyes). While the staining scheme of mFISH is identical, HiSKY's measurement scheme is very different than the one used in mFISH, which is basically standard FISH acquisition done using multiple microscope filters.
This lets cytogeneticists intuitively find chromosomal abnormalities they might not have discovered otherwise. HiSKY is the cytogenetics workstation based on the SKY technique. The fact that HiSKY measures the entire spectrum at each point enables to completely extract the exact emission of each dye. No errors due to cross talk, high background or wrong contrast of specific layers. Here the power of HiSKY is seen in its full glory. The outcome is a robust classification, which is the reason why consistently HiSKY is the choice even for the routine clinical lab.
The level of automation of a system also influences the accuracy, repeatability and mainly the throughput. HISKY is fully automatic, from the acquisition stage right through to the analysis and verification.
Hundreds of scientific publications (over 700) have been written by SKY users revealing new information clarifying and correcting the prognosis and treatment for people all over the world. AIS is an exclusive distributor of ASI in Australia and New Zealand.