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Scientist Uses Laser to Learn About Interaction between Glutamate and Transport Protein

Christof Grewer, a researcher from Binghamton University, is figuring out a critical brain transport protein.

He is currently utilizing a traditional approach to spy on the glutamate transporter protein by aiming with lasers. Glutamate, known to be a critical molecule for cellular metabolism, also acts as a neurotransmitter.

Scientists recognize the importance of transport proteins. They also acknowledge the fact that transport proteins move the glutamate through the cell wall. But scientists have not been able to find out as to what triggers the transport proteins to move the glutamate to the outside or inside of a cell. Finding the functioning of the triggers can facilitate in providing vital implications on human health. During the occurrence of a stroke, when oxygen and blood are restricted to the brain, the cells discharge glutamate into the surrounding space. This initiates a toxic chain, which can damage brain functions and kill brain cells. By learning the transportation of glutamate molecules, scientists can develop drugs that halt or help the glutamate transportation.

Grewer has created a technique that utilizes lasers to kick start the transportation function. He can document the transportation by controlling the movement of the glutamate molecules. Tracking the movement will pave the way for better understanding of the transportation between glutamate molecules and transporters. Grewer learnt about glutamate receptors during his fellowship course at Cornell University. He stated that he has been trying to stimulate the receptors on a rapid time scale.

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