Jul 30 2010
Bodkin Design & Engineering, in collaboration with Zoίray Technologies and Boston University, has developed a commercial biosensor instrument from its research. The SRIB (Spectral Reflectance Imaging Biosensor) is a multiplexed immunoassay device useful for clinical diagnostics and life science researches.
Bodkin SBIR
Immunoassays are used to detect particular protein biomarkers in saliva, urine, or blood. Zoíray’s technology helps to multiply many immunoassays in a compact disposable chip. The final design of the SRIB includes a digital control, fluidics, high-resolution camera, and a class IIIb tunable laser. The biosensor device carries out data analysis, specimen disposal, optical interrogation, reagent introduction, and specimen delivery automatically, all in one small tabletop unit.
A biochip with active proteins is filled into the SRIB during operation. Then the device is prompted to provide the reagents and specimen to the reaction flow cell. The incubation happens in the flow cell, after which the sample is probed optically with the use of laser and then evaluated. The system captures several interactions at the same time and analyzes them with the help of computer and the inbuilt camera.
Zoίray’s CEO, Dr. David A. Bergstein, commented that Bodkin Design had created many approaches that offered measurement sensitivity, ease-of-use, and manufacturing costs equally to reach an optimal solution for pushing the protein array sensor into the market.